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Sex refers to the male and female duality of biology and reproduction.  Unlike organisms that only have the ability to reproduce asexually, sexed male and female pairs have the ability to produce offspring through meiosis (self reproduction by dividing cells) and fertilization. The two sexes attract one another and communicate their readiness to procreate through differences in their biology.

In humans, "sex" is often perceived as a dichotomous state or identity for most biological and social purposes - such that a person can only be female or male. But many factors, including one's biology, environment, psychology and social context, have a role in determining how a particular person, and those around them, view their sex.

"Primary" sexual characteristics are typically present at birth and directly involved in reproduction. "Secondary" sexual characteristics typically develop later in life (usually during puberty) and are not directly involved in reproduction. Differences between the sexes are known as sexual dimorphism.